University of Wisconsin Solution (UW) Segment Held Largest Share of Organ Preservation Solution Market

According to our latest study on "Organ Preservation Solution Market Forecast to 2028 - COVID-19 Impact and Global Analysis - by, Type, Application, Organ Type, and End User," the market was valued at US$ 255,917.42 million in 2022 and is expected to reach US$ 399,497.49 million; it is estimated to register a CAGR of 7.8% from 2023 to 2028The report highlights the key factors and trends impacting the market and focuses on prominent players and their strategies.

Organ transplantation is one the fastest developing medical procedures, and few of the most commonly donated and implanted organs are heart, liver, kidney, lungs, and tissues. Cardiovascular disorders are heart and blood vessel disorders, which include cerebrovascular diseases, coronary heart disease, rheumatic heart disease, etc. Tobacco use, unhealthy diet, and physical inactivity, which increase the risk of heart attacks and strokes, are a few of the major causes of death. 

Cardiovascular diseases are becoming increasingly prevalent across the globe. Cardiovascular diseases are the world's leading cause of death. According to the CDC, in the US, heart disease is the leading cause of death for men, women, and people of most racial and ethnic groups. In 2020, ~697,000 people died from heart disease, i.e., one person dies every 34 seconds from cardiovascular disease, i.e., 1 in every 5 deaths. Most CVD deaths are followed by a stroke and heart failure due to coronary heart disease (CHD). CVD is diagnosed in ~90 million Americans. It is also stated that approximately 31% of all deaths are caused by cardiovascular diseases worldwide. According to organdonor.gov, the heart is the third-largest vital organ transplantation performed after kidney and liver. Further, new technologies for a heart transplant are expected to offer lucrative opportunities for the organ preservation solutions market in the coming years. For instance, in September 2021, FDA approved the Transmedics Organ Care System (OCS) Heart or "Heart in a Box," which enables transplant doctors to travel to different locations to collect transplant hearts as the system acts as a miniature intensive care unit that maintains the heart's viability. Moreover, as per the American Heart Association, in 2020, approximately 19.1 million deaths were attributed to CVD globally. Therefore, the increasing need for a heart transplant, owing to the increasing prevalence of cardiovascular diseases, is expected to boost the organ preservation solution market growth during the forecast period.

Based on application, the organ preservation solution market is segmented into static cold storage, hypothermic machine perfusion, normothermic machine perfusion, and others. The static cold storage segment accounted for the largest market share in 2022. However, the normothermic machine perfusion segment is expected to register the highest CAGR of the organ preservation solution market during the forecast period. Normothermic machine perfusion is based on the recreation of the physiological environment through the preservation of natural organ temperatures and the requisite substrates for cell metabolism, oxygen, and nutrition. Pulsive perfusion of oxygenated blood, controlled by temperature and pressure, increases cell energy and post-transplant graft reduces tissue damage. Although normative donor perfusion has theoretically gained a reputation for more than a hundred years, new technology has been developed for the conservation and transit of organs. Several clinical trials have been conducted to demonstrate the effectiveness of this method as a pre-transplant organ conservation tool. For example, PROCEED II was a multicenter, multinational research project, which began in 2009 and was completed in 2013. The test showed the SCS technique to secure donor hearts for transplantation by contrasting the Organ Care Process (a normothermal organ preservation solution developed by Transmedics, Inc.). The results of the study showed that normal thermal cardiac infusion resulted in cold ischemic times relative to SCS during transport. It also indicated that normal thermal perfusion appears to extend the period for organ retrieval, which increases the donor pool. The study also showed that the normative system perfusion technique helps the implanting surgeon to assess the efficacy of the donor organ. 

Waters Medical Systems LLC; XVIVO Perfusion; TransMedics; OrganOx Limited; Paragonix Technologies, Inc; Dr. Franz Koehler Chemie GmbH; Accord Healthcare; 21ST CENTURY MEDICINE; Shanghai Genext Pharmaceutical Technology; Bridge to Life Ltd; Perfusion Solutions, Inc.; and Lifeline Scientific are among the key players operating in the organ preservation solution market.

The report segments the organ preservation solution market as follows:

The global organ preservation solution market is segmented on the basis of type, application, organ type, and end user. Based on type, the market is classified into University of Wisconsin solution (UW), custodiol HTK, perfadex, hypothermosol, and others. Based on application, the organ preservation solution market is segmented into static cold storage, hypothermic machine perfusion, normothermic machine perfusion, and others. Based on organ type, the organ preservation solution market is segmented into kidney, liver, lung, heart, and others. Based on end user, the market is segmented into organ transplant centers, hospitals, and specialty clinics.

Based on geography, the organ preservation solution market is segmented into North America (US, Canada, and Mexico), Europe (UK, Germany, France, Italy, Spain, and Rest of Europe), Asia Pacific (China, Japan, India, Australia, South Korea, and Rest of Asia Pacific), the Middle East & Africa (UAE, Saudi Arabia, South Africa, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America). 

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